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Audiovisual Processing is Abnormal in Parkinson’s Disease and Correlates with Freezing of Gait and Disease Duration

Background; Sensory and perceptual disturbances are prominent in Parkinson’s PD and probably contribute to motor deficits such as bradykinesia and gait disturbances, including freezing of gait. Simple reaction time tests are a helpful way to explore …

Atypical multisensory integration in Niemann-Pick type C disease – towards potential biomarkers

Niemann-Pick type C (NPC) is an autosomal recessive disease in which cholesterol and glycosphingolipids accumulate in lysosomes due to aberrant cell-transport mechanisms. It is characterized by progressive and ultimately terminal neurological …

Ready, Set, Reset; Stimulus-Locked Periodicity in Behavioral Performance Demonstrates the Consequences of Cross-Sensory Phase Rese

The simultaneous presentation of a stimulus in one sensory modality often enhances target detection in another sensory modality, but the neural mechanisms that govern these effects are still under investigation. Here, we test a hypothesis proposed in …

Auditory facilitation of visual-target detection persists regardless of retinal eccentricity and despite wide audiovisual misalignments

It is well established that sounds can enhance visual-target detection, but the mechanisms that govern these cross-sensory effects, as well as the neural pathways involved, are largely unknown. Here, we tested behavioral predictions stemming from the …